Dynamic changes in neutrophil activation and metabolic profile during pregnancy are associated with gingival inflammation
Fecha de Publicación: Octubre 2025 Referencia https://www.nature.com/srep/ Resumen general Neutrophils are key players in both periodontal and placental immunity, undergoing profound immunometabolic and functional changes during pregnancy. Their excessive activation has been linked to gestational complications. Gingivitis, and even more so periodontitis, the advanced stage of this condition, are chronic inflammatory diseases that frequently worsen during pregnancy and have been associated with adverse outcomes
Pregnancy Entails a Metabolic Rewiring of Maternal Circulating Neutrophils
Fecha de Publicación: Enero 2025 Referencia J Cell Physiol. 2025 Jan;240(1):e31502. doi: 10.1002/jcp.31502. Epub 2024 Dec 16. Resumen general Immunometabolism is an emerging growing field that focuses on the role of cellular metabolism in the regulation of immune cell function and fate. Thus, proliferation, differentiation, activation, and function of immune cell populations are modulated by reprogramming their fueling and metabolic pathways. Pregnancy entails a fine